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Most importantly, the Aβ42 K16N peptide alone is almost non-toxic and only gains severe toxicity when it is mixed with its wild-type (WT) counterpart.
Among the 17β-acetamido-B-lactamic steroidal esters, the most potent compound afforded four out of six cures in leukemia P388 and was measured to be almost non-toxic, producing significant low levels of toxicity.
These results confirmed that SA-FSNPs were almost non-toxic to the main organs, showing the potential to be clinically useful as a diagnostic probe.
Some could find reasonable application in algicides (Ag and CuO) or antimicrobial surfaces (Pd, Ag and CuO), while Au and Pt proved to be almost non-toxic to green alga C. reinhardtii.
The cytotoxicity of these nanoparticles depends on their shape, size, surface chemistry, etc., as spherical silver nanoparticles and microparticles are almost non-toxic to human alveolar epithelial cells, while silver wires shows strong cytotoxicity against it [98].
However, the gamma radiation of 67Ga used in scintigraphy is considered to be almost non-toxic to lymphoma cells.
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LNA ASO was found to be almost non toxic, with more than 85% of the cells being viable after 48h of incubation with 10 and 25 nM LNA ASO (Figure 6).
They are zero emissions vehicles, completely non-toxic, silent, almost 100% recyclable, and get the equivalent of 455 miles per gallon.
In contrast, chronic intermittent injections of non-toxic METH doses provided almost complete protection against striatal DA depletion and against decreases in TH protein levels induced by toxic METH challenges.
Even after 48 h of incubation, the formulations appeared to be non-toxic upto very high concentrations of almost 800 μM.
The use of water in loop heat pipes (LHP) is known to be desirable: water is almost freely available; it exhibits high thermal performance and is non-toxic.
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