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All eight SNPs were in almost complete linkage disequilibrium.
Since these 2 SNPs were in almost complete linkage disequilibrium (LD) (r2 = 0.98 in this population and r2 = 1 in HapMap-CHB population), only the rs6234 was selected for further association analyses as it had a higher genotyping success rate.
The ADH1C and272Gln and Ile350Val showed almost complete linkage.
There is almost complete linkage disequilibrium (Lewontin D' = 0.95) between the rs20417 polymorphism 5' of PTGS2 and rs5275 of of PTGS2.
The BsmI (G → A) polymorphism was in partial linkage disequilibrium with the ApaI (G → T) polymorphism (|D'| = 0.964; r = 0.330), and in almost complete linkage disequilibrium with the TaqI (T → C) polymorphism (|D'| = 0.919; r = 0.807).
IGF2BP2 rs1470579 C was not further analyzed, as it was found to be in almost complete linkage disequilibrium with IGF2BP2 rs4402960 T (D′ = 1.0, r = 0.981), forming a common haplotype that includes minor alleles for both loci.
Similar(46)
First, we show that the HA1 domain of influenza evolves under almost complete genetic linkage, which can be quantified by allele frequency correlations between polymorphic sequence sites.
Hence, epitope and non-epitope sites of the HA1 sequence evolve in a genuinely asexual way, that is, under almost complete genetic linkage.
Universal health care coverage in Italy allows completeness and comprehensiveness of the information contained in these databases, which in a previous epidemiological study showed almost complete (>95%) linkage.
The participant rate was high and the follow-up up to 34 years almost complete through using linkage to national registers with high coverage.
This dataset is said to contain almost complete information on linkages among Japanese firms.
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