During the eight weeks observation period the application of a hollow chamber design resulted in almost complete cranial defect healing, whereby the copolymer composition had no effect on the amount or the morphology of the regenerate.
Apparent recovery of the macroscopic shape and bio-mineralization of BAp was almost complete in the ulna defect after 4 weeks.
Results indicate that the amount of bone in the positive controls is greater than in the negative controls suggesting almost complete healing of the defect.
Strikingly, an almost complete rescue of all defects, including body morphology (non-inflated wings and "slimy" body wall), locomotion, climbing activity and lifespan was obtained when we used a pan-neuronal (elav-Gal4) (Luo et al., 1994) or adult nervous system DJ684-Gal44) (Setoude et al., 2002) Gal4 drivers (Fig. 2C,D).
Defect almost completely covered with cartilage-like tissue Almost complete bone repair The repair tissue surface was assessed using MRI, while the subchondral tissue was assessed using MRI and CT.
Indeed, Scrib Crc/Crc mutants exhibited almost complete penetrance of abdominal wall defect (98%, n=50/51 at E14.5 or older), whereas less than 10% of Celsr1 Crsh/Crsh and less than 5% of Vangl2 Lp/Lp homozygotes had this defect.
Compared with the control group, single-cell stage injection of 2 ng pax1b MO caused moderate defects, with smaller and asymmetric pectoral fin in 55% of embryos, and severe defects including the almost complete lack of fin buds in 27% of embryos.
MRI showed a marked surface depression in the empty defects while defect filling in the ADTT group was almost complete with repair tissue resembling healthy cartilage.
The visual field loss caused by glaucoma has been divided into 5 stages ranging from relative defects in sensitivity to almost complete visual loss [ 1].
Thus, results indicate that such Co-dopedZnO thin films are chemically purer and have many fewer defects and lessdisorder, owing to an almost complete chemical decomposition.
