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Given that mixed tetramers between wild-type p53 and p63 proteins do not form 12 but p63 homotetramers do, we speculate that this reflects the fact that the bulky Hprt tag might impair direct DNA binding of ΔN(3′-10 Hprt homotetramers, while it still allows to engage in mixed tetramers with TAp63γ, thereby acting as a stronger dominant negative.
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"When you write about sports, you're allowed to engage in mischief," he says.
Should African women be allowed to engage in the practice sometimes called female circumcision?
Thompson is in no doubt that young readers need to be allowed to engage with difficult material.
"It is apparent that the child should not have been allowed to engage in any active physical conduct," Mr. Levy said.
He also contends that children are only allowed to engage in work that will not interfere with their education.
She — and 2,000 other political prisoners — should be released immediately and allowed to engage in peaceful political activity.
Americans will not be allowed to engage in combat or launch operations from Colombia against a third country, they insist.
Clearly, lenders cannot be allowed to engage in practices that amount to fraud or that prey on Americans least equipped to defend themselves.
In China, all religious groups must be affiliated with government-controlled associations and are not allowed to engage in public efforts to spread their beliefs.
That could happen within the next couple of weeks, but even if that were to occur, he said, she would not be allowed to engage in political activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com