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Localized population record linkage allows screening of the thresholds for intervention and allows these to be reset in response to data on effective treatments.
Comparative genomic hybridisation (CGH) allows screening of the entire genome in order to identify regions of gain or loss of DNA and map them according to chromosomal location (Kallioniemi et al, 1992).
It is therefore important that cases are diagnosed to subtype level when the first cases are recognised to enable rapid development of genetic test that allows screening of the sire population.
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DNA microarrays currently allow screening of the entire human genome with high level of coverage and we are now entering the era of high-throughput sequencing.
HRM assays were developed to allow screening of the ryanodine receptor gene (RYR1) for potential mutations causing malignant hyperthermia (MH) and/or central core disease (CCD) using the LightCycler 480 System.
Due to the recent advances in next-generation sequencing technologies, the development of genomic tools (i.e. SNP-chip) of high to very high density will allow screening of the whole tomato genome for association with traits of interest.
The last items were aimed at the future expectations of the respondents concerning Magnetic Resonance-guided Focused Ultrasound (MRgFUS) as a new treatment alternative for uterine fibroids, and we asked if the treatment facility had a Web site to allow screening of the Web sites for dedicated information on UFE treatment.
Previous studies using liquid assays in microtiter plates were not high throughput enough to allow screening of the entire yeast genome [ 23], and although high throughput analysis has been achieved by others, that was only by pooling strains tagged with a specific DNA sequence 'bar-code'.
Hence, the zebrafish Danio rerio is gaining popularity in metabolic research and drug discovery, as this animal model allows screening of small molecules in the context of the whole-organism.
After completing many iterations of this process, involving the dissection and staining of embryos from more than 700 Df lines, we were able to define a new kit of 423 lines, which allows screening of 80 90% of the genome for Lar-AP staining, or staining with other reagents that recognize CNS axons.
The array allows screening of far more ligands than could be undertaken in a structural analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com