This technology allows for the limitation of the duration of Cas9 expression in a biallellic mutation in multiple target loci [ 69].
So, when therapy appears to be failing and the prognosis looks grim, withholding therapy may be preferable to withdrawing because it allows for the limitation of potentially inappropriate therapy while not irrevocably determining outcome.
Allowing for the limitations discussed below, our results indicate favorable effects of WB-EMS with respect to the regional shift of muscle and fat mass in the upper leg.
Even allowing for the limitations that are inherent in interpreting survey data, Cannesson and colleagues show us that practice remains out of sync with the current evidence base with regards to GDHT [ 1].
The probabilistic tractography technique used is less likely to underestimate the size of the tract in comparison to the more common deterministic tractography, and it may still be necessary to add a further safety zone to allow for the limitations of tractography and a surgical margin of error.
Allowing for the limitations of accuracy in death certification, the high rate of infection-related mortality in this study supports the hypothesis that adverse effects of therapy contribute to poor outcome and emphasizes the advantage of identifying patients with salvageable kidney function.
Allowing for the limitation of pressure loss in directional drilling, the design of fluidic jet oscillator is feasible to horizontal directional drilling to reduce friction and drag torque, which contributes to improving the penetration rate and reservoir development capacity in oil and natural gas well drilling.
Allowing for these limitations, the possibility that the findings are false positive cannot be completely excluded.
The analysis generated a useful taxonomy of potential barriers to accurate reporting of adverse events and, even allowing for the above limitations, showed the value of permitting access to data.
The study revealed that using Si/SiC material increases the production rate for carbide-derived carbons dramatically, due to higher reactive surface area and lower mass transfer limitations, which allows for the time effective production of larger monoliths.
