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The different means of action between ErbB2 and CSR allows for overlap of both these variables in determination of probability of survival.
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Using a metric that allows for overlapping annotations, we achieved machine-annotator agreements of 88.9% for phrase recognition and 91.9% for phrase-type identification (Action names).
Plaid [11] [13] is a form of two mode clustering that allows for overlapping clusters.
Note, however, that this assumption still allows for overlapping biclusters.
These distinctions are useful analytically but should be conceptualized on a continuum which allows for overlaps.
The key new feature of our model is that it allows for overlapping gene conversion events in the copying process.
The format thus allows for overlapping structures, in other words a given voxel index can be contained in multiple voxel lists.
And since proteins may belong to multiple cellular subsystems, an approach that allows for overlapping clusters is more appropriate than the one that partitions the data.
As proteins often perform multiple functions in a cell, we decided to use a clustering algorithm that allows for overlaps between different clusters, permitting individual proteins to be part of several different subnetworks.
The dimensionless spray flux approach of Hapgood et al. (Powder Technol. 141 (2004) 20) is extended to account for nonuniform spray patterns and allow for overlap of nuclei granules rather than spray drops.
The benefits of allowing for overlap among modules are documented by the good IC values of DECOBRA (recall the definition of IC as the probability that a gene / GO term combination is reflected by a module containing the gene and being enriched relative to the GO term), in both Yeast and Human.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com