The phrase "allows for destabilization" is correct and usable in written English.
It can be used in contexts discussing systems, structures, or processes that can be disrupted or made unstable.
Example: "The new policy allows for destabilization of the existing economic framework, leading to unforeseen consequences."
Alternatives: "facilitates destabilization" or "permits destabilization."
Little and Wright [ 5] developed a stochastic carcinogenesis model which allowed for genome destabilization, very close in spirit to the model of Mao et al. [ 130], and generalizing the class of generalized MVK models developed by Little [ 4, 123, 126], which in turn therefore generalize the two-mutation model of Moolgavkar, Venzon and Knudson [ 2, 3].
Since the first binding event redistributed C2B's ensemble, the C2A-induced destabilization allows for a different subset of conformers (which may have different molecular ramifications) to become more accessible compared with C2B's basal state ensemble.
Destabilization of these secondary structures at higher temperatures (37°C, as might occur within a host) allows for translation initiation and increased levels of PrfA.
The pulling force of Rca is fine-tuned to avoid global destabilization and allow for precise enzyme repair.
Indeed the simulations show that the monomer alone leads to membrane denting, but is apparently incapable of inducing ion permeation; we did not find evidence for sufficient destabilization of the membrane to allow for passive ion translocation.
Loss of A-type lamin is predicted to cause mis-localization of the Sun domain proteins and/or destabilization of the Sun-nesprin interactions, allowing for expansion of the perinuclear space.
Biochemical evidence suggests that BH3-only proteins can interact with and antagonize partially overlapping sub-sets of Bcl-2 homologues by direct interaction, allowing for activation of Bax and/or Bak, leading to their oligomerization, subsequent destabilization of mitochondrial integrity, release of apoptogenic factors, caspase activation and cell death (3).
"It allowed for continuity.
Implications and future directions This model will allow, for the first time, the use of unbiased forward and reverse genetic approaches in a live-animal setting to identify regulators of ΔF508-dependent protein destabilization.
Given how well some of these simpler models fit this data (e.g., the two cancer-stage one destabilization (2-1) model), it is perhaps unremarkable that Little et al. [ 6] do not find much improvement in fit offered by the models that allow for multiple types of GI.
