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The partial dual education system allows for a stepwise approach.
This allows for a stepwise growth pattern, with the possibility of dormant phases.
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Conventional (Sanger) sequencing facilities are expensive with very limited capacities and thus only allow for a stepwise approach dependent on mutation frequencies and the ethnic origin and phenotype of the patient.
The Integrated MNCH CHW Program's strategy of training an initial group of CHWs in each facility catchment area and later returning to train more may allow for a stepwise approach to implementation which eases the strain on facility providers and allows communities/MoHSW to identify candidates that meet eligibility criteria over time.
This stepwise, 'tag-free' approach allows for a significant reduction in molecular weight and polar surface area compared to full-length fluorescent or biotinylated probes, potentially enhancing membrane permeability and the maintenance of activity.
This allows for a better close.
There are many barriers to drug and gene delivery, yet the multifunctionality of nanoparticle systems allows for rational, stepwise optimizations for addressing these barriers.
Synaptotagmin therefore presumably allows for stepwise close apposition of SNAREs and fusing membranes.
Studies of the corresponding non-enzymatic reactions reveal a complex mechanistic landscape allowing for a variety of transition states and both concerted and stepwise mechanisms.
The decrease in intensity as the chain length increases is fitted to an exponential decay curve which then allows for the determination of a stepwise synthesis yield.
The MLMM employs stepwise mixed-model regression with forward inclusion and backward elimination, thus allowing for a more exhaustive search of a large model space.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com