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As discussed above, the eukaryotic cellular environment is more permissive for gene duplication, allowing duplicate genes to be partitioned to different cellular compartments to bypass the dosage evolutionary constraint.
In the conventional view, opportunities for adaptive specialization drive the expansion of gene families; in the DDC model, duplication creates a capacity for complementation of mutations that impair sub-functions, allowing duplicate pairs to stumble from redundancy to co-dependency, resulting in apparently specialized genes.
In this series of experiments approximately one fifth of the eluate was tested first, allowing duplicate amplifications to be performed on each sample to allow for systems diagnostics.
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Gene duplication is a major force of adaptive genome evolution, since it allows duplicate genes to explore different aspects of the multidimensional functional space [ 15].
But with Vetsnet, workers say, the technology has allowed duplicate records.
∎ Scripts have recently been developed to allow duplicates to be identified and addressed following each vaccination campaign.
Among the 38SH22 families, 33 possess at least one gene duplicate allowing a duplicate copy to acquire new functions such as specialized tissue functions or novel scaffolding capabilities [ 70].
CAMs were cut into 12 sections of approximately 0.1 g wet weight (mean = 0.104 g±0.0009 SEM) allowing for duplicate sections to undergo identical treatment regimes.
The editor was careless, allowing several duplicated recipes to sneak in.
Genetically, a lower constraint associated with these characteristics could allow nGPCR genes to better tolerate deleterious random mutations and accumulate beneficial mutations, thus allowing nGPCR duplicates to be fixed with a higher probability as compared to genes with average constraint (Fig. 6B).
Neofunctionalization hypothesizes that the presence of redundant copies of genes allows one duplicate to be free from selective pressure, and thus one of the duplicates can accumulate random mutations and potentially acquire novel functions [ 37].
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