Even small differences in allele frequency between bulks can be detected with this genotyping-by-sequencing approach (Parts et al. 2011), allowing detection of small effect variants.
Tumor organoids are amenable to high-throughput drug screens allowing detection of gene-drug associations.
We show that this reagent is complementary to antibody-based tools allowing detection of endogenous cellular proteins such as histones carrying the crotonylation PTM.
Here we demonstrate that this tight binding controls highly sensitive responses, allowing detection of urea concentrations as low as 50nMM.
Targeted profiling of 18,559 protein-coding genes by DriverMap resulted in 11.1 to 12.9 million aligned sequence fragments per sample (mean, 12.0 million), allowing detection of 13,182 genes.
Second, the placenta forms at a very early stage of embryonic development, potentially allowing detection of primary alterations as compared to secondary changes that may mask the underlying causal phenomena.
In an effort to design a selective assay allowing detection of free monomeric ubiquitin, an approach based on a C-terminally biotinylated form of ubiquitin is proposed.
Molecular diagnostic tests to detect enterovirus in clinical specimens usually target highly conserved sites in the 5′-non-translated region, allowing detection of all members of the genus.
Here we describe the design and evaluation of an oligonucleotide probe for chromogenic in situ hybridization, theoretically allowing detection of all hitherto known members of the order Trichomonadida.
SiC detectors recorded neutron counts during and immediately following the source neutron bursts, allowing detection of fission neutrons with short (120 μs) die-away times.
The assay is specific, allowing detection of only oleander-infecting strains, not other strains of X. fastidiosa nor other plant-associated bacteria tested.
