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Given the difficulty of the ligand accessing all of the receptors in vesicular cell membrane preparations or in intact cells, our group elected to use a Jun zipper to clamp all receptors in particular alignments, allowing consequence of this on proliferative signalling to be observed, while monitoring the positioning of FRET reporters placed close to the Box1 motif in parrallel [ 44, 51].
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Mr. Spitzer and many other powerful men like him do not even allow the consequences of their acts to interfere with their testosterone rush for a single minute.
Instead of italicizing the importance of this moment in history, he allows the consequences of this clash of civilizations to bubble up slowly through his characters' stories.
The AFM's ability to examine the composition of a predominantly single gene product population at the level of the single molecule allows the consequences of post-translational process heterogeneity to be examined at high resolution.
The model allowed functional consequences of SCD mutations to be assessed and likely substrates identified that may offer novel therapeutic approaches.
As Cizik puts it, "We cannot love our neighbor if we allow the consequences of climate change, pollution, habitat destruction, species extinction, and the spread of human infection diseases to go unabated".
QALYs quantify patients' health-related utility on a scale from 0 (dead) to 1 (perfect health) allowing the health consequence of any clinical condition to be compared [ 16].
We must not allow an unintended consequence of the recent surge in faith schools to be the propagation of suspicion and hostility between different faith communities.
And we allow no individual consequence of any proportionality to the transgression.
This is necessary to allow the functional consequence of these variants to be analyzed before a drug is prescribed.
There is a palpable sense of exhilaration, and also a trepidation, perhaps a natural consequence of allowing a third party, however familiar, into a private space.
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