Steel-making and the use of the "blast furnace," developed in 1855 by Henry Bessemer, allowed for the large-scale production of strong and cheap steel, which became the material of choice for artillery, guns, and warships.
The availability of these mature, Open packages allow for the large-scale extraction of chemical data from the published literature.
Proteomics technologies allow for the large-scale scanning of proteins.
The result is a novel, practical and precise mathematical framework, that allows for the large-scale analysis and unbiased comparison of PPINs from different species and measured with different techniques.
In particular, recent advances in the experimental technologies which allow for the large-scale screening of the effects of combinatorial gene deletions are providing an exciting glimpse into the organization of complex genetic networks in terms of revealing novel interacting cellular components and compensatory pathways involved in many cell functions.
Nevertheless, natural selection can be expected to lead to adaptations influencing behaviors that are most advantageous to prey capture [ 1], and further examination of the molecular mechanisms allowing for these large scale behavioral adaptations is critical for understanding coevolution between predator-prey interactions.
The 454-EST resource allowed for the first large-scale acquisition of ESTs from H. serrata and P. carinatus, which are representative members of the Huperziaceae family.
Having demonstrated the specificity and efficiency of CAPPIA, we next explored whether this method allows the large scale screening for hormone-dependent interactions.
Microarray technologies have also allowed for rapid and large scale studies on gene presence/absence in a large number of isolates, including in Salmonella [ 17].
These algorithms identified codon-triplets context biases, allowed for large scale comparative codon-triplet analysis, and identified rules governing codon-triplet context.
