Sentence examples for allow variant from inspiring English sources

Massive parallel genomic sequencing approaches allow variant detection that is not captured by gene array methods.

In contrast, currently available tools only allow variant level evaluation and these tools are more suitable for panel-based genetic testing where only known disease genes are tested.

Results were exported to Human Genome Variation Society nomenclature and converted to hg19 genomic coordinates using Mutalyzer 2.0 β-8, (http://www.mutalyzer.nl/) to allow variant annotation using ANNOVAR (Wildeman et al, 2008; Wang et al, 2010).

Site assignment of methionine oxidation using this workflow has two major drawbacks: (1) a substantial amount of sample is required to allow variant fractionation and subsequent peptide mapping (especially for low abundant variants) and (2) the procedure is time consuming, due to elongated sample preparation and LC-MS analysis.

Recombination can allow variants of a population to escape from the current fitness peak (escape from Muller's ratchet) and re-appear with a new phenotypic make-up and/or even re-establish in a new host-relationship [ 7, 8].

In cycles 8 and 9, the chamber temperature was not varied significantly in order to allow variants that can grow rapidly at this temperature to take over the population.

One allowed variant is the caffelatte, usually served in a tall glass, with extra milk added.

The design automation is coupled to an evaluation tool that allows variant selection regarding product and process characteristics such as power, energy or ease of assembly.

This approach allows variant calls at a particular genomic position to be reconciled across the pedigree, potentially correcting calls lying near the cutoff for a single individual.

We then used a probabilistic model allowing variant validation and attribution of a confidence level for each genotype based on several objective criteria.

The coefficients for the rare variants are estimated from the data, allowing variants to have both risk and protective effects.