We adapted this assay to allow screening of mutant libraries of either l- or d-amino acid specific aminotransferases in a continuous fashion.
DNA microarrays currently allow screening of the entire human genome with high level of coverage and we are now entering the era of high-throughput sequencing.
The load-balancing, fault-tolerance, and scalability in MapReduce allow screening of very large conformation spaces not approachable with traditional clustering methods.
Chris Yates, an aviation analyst, said airports were also dragging their feet over investing in new technology that would allow screening of suspicious liquids, at a cost of up to £100,000 per machine.
In principle, efficacy of biomaterial development for the cell cultures can be improved by using high-throughput techniques that allow screening of a large number of materials and manipulate microenvironments in a controlled manner.
Labeling with soluble ligands enables rapid and quantitative analysis of yeast-displayed libraries by flow cytometry, while cell-surface selections allow screening of libraries with insoluble or even as-yet-uncharacterized binding targets.
HRM assays were developed to allow screening of the ryanodine receptor gene (RYR1) for potential mutations causing malignant hyperthermia (MH) and/or central core disease (CCD) using the LightCycler 480 System.
Their effect on TNFα-induced cytokine secretion in HT29-19A epithelial cells was tested using Raybio® membranes that allow screening of a large panel of inflammatory factors.
Additionally, the eGFP-based readout will allow screening of millions of candidates (through rational or non-rational based approaches) in a single experiment, with extreme sensitivity.
These programs rely on the use of tools that allow screening of a large number of samples at a reduced cost.
