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DNA microarrays currently allow screening of the entire human genome with high level of coverage and we are now entering the era of high-throughput sequencing.
HRM assays were developed to allow screening of the ryanodine receptor gene (RYR1) for potential mutations causing malignant hyperthermia (MH) and/or central core disease (CCD) using the LightCycler 480 System.
Due to the recent advances in next-generation sequencing technologies, the development of genomic tools (i.e. SNP-chip) of high to very high density will allow screening of the whole tomato genome for association with traits of interest.
The last items were aimed at the future expectations of the respondents concerning Magnetic Resonance-guided Focused Ultrasound (MRgFUS) as a new treatment alternative for uterine fibroids, and we asked if the treatment facility had a Web site to allow screening of the Web sites for dedicated information on UFE treatment.
Previous studies using liquid assays in microtiter plates were not high throughput enough to allow screening of the entire yeast genome [ 23], and although high throughput analysis has been achieved by others, that was only by pooling strains tagged with a specific DNA sequence 'bar-code'.
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Localized population record linkage allows screening of the thresholds for intervention and allows these to be reset in response to data on effective treatments.
It is therefore important that cases are diagnosed to subtype level when the first cases are recognised to enable rapid development of genetic test that allows screening of the sire population.
Comparative genomic hybridisation (CGH) allows screening of the entire genome in order to identify regions of gain or loss of DNA and map them according to chromosomal location (Kallioniemi et al, 1992).
The development of a suitable blood test that would allow screening of large numbers of the population would prove extremely valuable in further quantifying the risk to the Irish population to vCJD.
We considerably selected a private school with a small number of students in order to allow screening of all children from the selected school in a single day.
Hence, the zebrafish Danio rerio is gaining popularity in metabolic research and drug discovery, as this animal model allows screening of small molecules in the context of the whole-organism.
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