Exact(4)
Finally, the results obtained in the present study would allow further optimization of flexible film sensors.
Finally, structure-based methods for sequence engineering [31], [32] may be implemented into this approach to identify replaceable positions and to limit libraries to manageable ensembles, which would allow further optimization of protein stability.
For example, exploring topoisomerase II isozyme selectivity, investigating the sensitivity and resistance of topoisomerase II mutants to voreloxin and analogs, and possibly mapping the sites of drug enzyme interaction may allow further optimization of topoisomerase II-targeting therapeutics to enhance clinical benefit.
Therefore, in screening programs that require a high volume of output and rapid turnaround, pilot studies that allow further optimization for the classes of compounds to be tested and for the desired characteristics of the actives may be necessary.
Similar(56)
Time sharing between different tasks running on the processor allowed further optimization in the memory system by increasing the memory reuse option.
The results presented here provide a foundation for subsequent, sequential optimization using narrower parameter ranges, allowing further optimization of the hydrolysis conditions and potentially enabling higher yield.
Docking experiments into the yeast 20S proteasome rationalized their biological activities and allowed further optimization of this interesting class of inhibitors.
Screens for small molecules and microRNAs that enhance cardiac reprogramming have revealed new insights into the mechanistic basis of this process and have allowed further optimization in human cells.
Careful study of the features and natural sampling of sequence space allows further optimization of peptide-indexing based look-up methods as oligopeptides reaching a database-specific critical length can become characteristic for a protein and its family of related sequences (see Supplementary Material).
For a system with significant parameter variations or containing moderate damping, a modified command design scheme and an on-line tuning scheme is proposed and demonstrated to allow further performance optimization.
These cases allow further NP optimization by the increase of laser heating ∆T0/E0 (Eqs. 4 and 12) and acoustic p/E0 (Eq. 7) efficacies and selection of thermo-optical and acoustic parameters (by increasing NP size or using ambiences with low sound speed).
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