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The pendant amine groups allow functionalization of the intermediate layers with eosin for subsequent photopolymerization of new hydrogel layers.
MOFs offer several advantages as electrocatalysts, electrolyte membranes, and fuel storage materials – they possess remarkable design flexibility, ultra-large surface-to-volume ratios, and they allow functionalization with multivalent ligands and metal centers to increase avidity for fuel cells.
BS3 cross-linker (Thamake et al. 2011) was added to allow functionalization of aptamer on to the surface of the nanoparticle.
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The well-known chemistry on Au surface allowed functionalization of Au NWs with self-assembled monolayers containing diverse functional groups.
Addition of an electrophile such as bromo-decanoic acid allows functionalization of the tubes.
Non-viral delivery systems are highly customizable, allowing functionalization to improve cellular and nuclear uptake, bypassing cellular degradative machinery, and improving gene expression in the nucleus.
In an effort to improve the selectivity of this chemotype, we switched to the pyrrolopyrimidine core which allowed functionalization on C-2.
In compound 2, the carboxylate anion of Rh101 was replaced by an alkyne moiety to allow further functionalization.
Passivating cell-mimics' polymer membranes with PEG, we showed that their membranes could be chemically modified, which will allow further functionalization, for example, for immobilization on substrates, to target specific proteins to the membrane or to tune membrane permeability.
Recently, gold nanoparticles (Au NPs) have gained much attention as model drug delivery platforms because of their advantageous surface characteristics that allow easy functionalization with chemical and biological molecules and also due to their apparently low toxicity.
The use of VNPs has evolved rapidly since their introduction 20 years ago, encompassing numerous chemistries and modification strategies that allow the functionalization of VNPs with imaging reagents, targeting ligands, and therapeutic molecules.
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