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Stepwise mutation models, which allow for stepwise changes of repeat size of alleles, have been extensively used to study MSs.
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Synaptotagmin therefore presumably allows for stepwise close apposition of SNAREs and fusing membranes.
The arrangement of recognition sites allowed for stepwise and seamless elongation of repetitive sequences.
Like the chambers used by other researchers, our design provides a fairly confined environment while allowing for stepwise additions of different sample solutions.
Unlike the 1-2-3 study, which reported findings across individual treatment groups receiving different numbers of injections, the design of the OSIRIS (Opposing Step-by-step Insulin Reinforcement to Intensified Strategy) study allowed for stepwise intensification from one to three doses of prandial insulin within an individual treatment group 35.
Conventional (Sanger) sequencing facilities are expensive with very limited capacities and thus only allow for a stepwise approach dependent on mutation frequencies and the ethnic origin and phenotype of the patient.
The Integrated MNCH CHW Program's strategy of training an initial group of CHWs in each facility catchment area and later returning to train more may allow for a stepwise approach to implementation which eases the strain on facility providers and allows communities/MoHSW to identify candidates that meet eligibility criteria over time.
The ultimate goal of contract-based design is to allow for compositional reasoning, stepwise refinement, and a principled reuse of components that are already pre-designed, or designed independently.
Another potential of this type of modification lies in the combined prefunctionalization together with amino (and, in principle, also with alkyne) moieties of the same RNA to allow for selective and stepwise attachment of sensitive moieties that cannot be directly incorporated into RNA.
The partial dual education system allows for a stepwise approach.
This allows for a stepwise growth pattern, with the possibility of dormant phases.
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