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These potential sites were further filtered for 35 bp of invariant sequence on each side to allow for probe design.
Roughly 693,000 variants were identified using GATK2 (McKenna et al. 2010) Haplotype Caller using default settings, then filtered for depth of coverage (minimum 7x), quality (minimum variant phred score 25), missing data (maximum missing 20%), and 35 bp of invariant sequence on each side to allow for probe design.
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The small-angle capability of the new Super High Momentum Spectrometer (SHMS) in Hall C, coupled with its high momentum reach – up to the anticipated 11-GeV beam energy in Hall C – and coincidence capability with the well-understood High Momentum Spectrometer (HMS), will allow for probes of such hadron structure involving strangeness down to the smallest distance scales to date.
It doesn't allow for probing of the gums to look for the presence of deepening periodontal pockets or bone destruction resulting from gum disease.
The zero expectation can be made without loss of generality because we allow for probe-specific offset terms (i.e. intercepts), which absorb any systematic deviation from these intensity−dependent functions.
The responses were both closed and open-ended questions to allow for probing of responses.
The identified piRNA clusters allow for probing the characteristics of these sequences compared to the rest of the genome.
For exploratory interviews, the number of questions is relatively small to allow for probing into details of the patient's experience.
The schedule served as a guide only, to allow for probing questions which were usually asked to seek clarification from respondents about their responses.
Improvements in performing core biochemical techniques (i.e. ChIP-seq, methyl-seq, RNA-seq) along with zebrafish cell lines and antibodies will potentially allow for probing of how epigenetic changes contribute to cancer phenotypes.
The second part of the interview followed an unstructured format to allow for probing and further questioning of ideas or individual circumstances that were not included in the original interview outline.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com