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The system is designed to be flexible and allow for facile incorporation of a variety of targeting ligands.
We show that these chemically different basal surfaces allow for facile selective modification making them compatible with e.g. polystyrene (PS) and poly methyl methacrylate) (PMMA), respectively.
Here, it is demonstrated that the rheological properties of these hydrogels allow for facile injectability, an increase of cell viability after injection when compared to cell viabilities of cells injected in phosphate-buffered saline, and homogeneous cell suspensions that do not settle.
We believe that an ideal chemical representation would require no specialized wrapper or interpreter, would be generic such as to allow for facile and conflict-free extensions, would be based on a formal ontology, and would be encoded in a machine-understandable (as opposed to simply machine-readable, as in CML) manner and therefore facilitates automated reasoning and data integration.
Autoradiography methods allow for facile measurement of tracer association or dissociation rates, and "no-wash" protocols are predictive of in vivo nonspecific binding.
MayaFluors are readily accessible in good yields in a one-pot, two-step approach starting from well-established BODIPY dyes, and allow for facile modification with functional groups of relevance to bioconjugate chemistry and bioorthogonal labeling.
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This versatile protocol allows for facile access to a wide range of important β-fluoroalkyl ketones from simple starting materials.
In addition, this platform for adenoviral modification allows for facile introduction of alternative targeting ligands.
The modified route allows for facile reaction workups, increased yields, lower cost and incorporates a green alternative step.
The continuous extraction in a membrane contactor allows for facile recovery of the fluorous tagged species in a scaleable operation.
Vapor-phase polymerization allowed for facile coating of the nanoscale layer in a relatively short processing time (30 min).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com