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Synthetic routes were devised to allow for array synthesis in which all three points of diversity could be facilely explored.
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We aimed for the construction of a miRNA expression library that fulfills four criteria: 1) the library contains all human miRNAs; 2) each miRNA is represented in a separate stock to allow for arrayed screening; 3) the library can be used over a wide range of different cell types; 4) the miRNAs are swiftly and stably overexpressed.
Positive and negative controls spotted within each array allow for assay validation.
The diversity of the region soaring mountains leading to beautiful coastlines and the densest vegetation of the Amazonian jungle allow for an array of products and ingredients to be produced, "providing a wealth of culinary adventures to visitors".
Legislative mandates to the practice of medicine do not allow for the infinite array of exceptions where the mandate may be unnecessary, inappropriate, or even harmful to an individual patient....Lawmakers would also do well to remember that patient autonomy as well as individual needs, values, and preferences must be respected".
To allow for comparisons between arrays, we used Gquantile normalization.
This method allowed for "between array" normalization, which aimed to enhance the comparability of signal ranges between replicate arrays by defining the final intensity of probes within a specific quantile as the average value of this quantile.
Arrays with sufficient within-array replication allow for the calculation of gene and array CVs that are useful in estimating the quality of the information gathered from a given array.
The court said the regulation allows for an array of cleanup options.
Senate procedure rules allowed for an array of useful tactics, such as stalling a bill with a swarm of amendments.
The open-ended rules -- submissions could be color or black and white, film or digital, journalistic or artistic -- allowed for an array of techniques and styles, but the photographs that caught our attention all shared fundamental traits: an original vision combined with magnificent execution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com