These methods where chemistry and process are strongly coupled, allow directing the assembling of a large variety of molecular precursors, oligomers, clusters or nanoparticles (nanobuilding blocks) into functional hierarchical structures.
The reactions on each pad are digitally controlled and allow directing the synthesis of oligonucleotides.
By their recruitment to the membrane, these proteins allow directing a pathway towards a specific target at a specific location and dramatically amplify the activation of this target.
To increase the versatility of this approach, we are now testing the capacity of other muNS domains (2, 4 and 1a) to function as molecular tags for directing proteins to inclusions, which would allow directing proteins containing different tags to the same inclusion.
This may allow directing the Hsp90 machinery to specific functions and a subset of its clientele.
A "talk aloud" usability study would both (1) allow directing a participant to select all aspects of the site and (2) gain insights into participants' choices of clinical summary format and insights into their clinical reasoning.
