31 For reimbursement agencies, the QALY has the advantage of allowing cost effectiveness comparisons between interventions for disparate health conditions.
The two core models described above 48, 53 were adapted by implementing local resource use and costs to allow cost-effectiveness analyses reflecting different country situations.
The use of QALYs would therefore allow cost-effectiveness analyses of obesity interventions to be directly compared to other childhood health interventions for obesity or other conditions.
This allows cost-effectiveness outputs to be expressed as a probability distribution rather than as a single point estimate.
The net benefit regression framework (NBRF) allows cost-effectiveness analysis to be done in a simple regression framework.
Our approach allows cost-effectiveness results to be presented for patients with characteristics relevant to a more general population with severe sepsis.
Finally, costs will be determined from a societal viewpoint to allow for cost effectiveness calculations.
This information will allow the cost effectiveness of HPV immunisation programmes to be quantified more accurately.
Stochastic analyses such as this will allow a cost effectiveness acceptability curve to be generated.
The group size was too limited to allow reliable cost effectiveness analyses in subgroups, so conclusions about subgroups should be considered as preliminary.
Comparison with no treatment allows the cost effectiveness of this model of CTC to be compared with any other intervention in health, and not just to be considered as an incremental change to alternative nutrition strategies [ 15, 29].
