Exact(1)
HATs are responsible mainly for destabilizing the chromatin structure to allow accessibility of different transcription factors, including NF-kB to the transcriptional site in the DNA.
Similar(59)
It is possible that sustained expression of genes like emx2 into post-embryonic and larval stages allows accessibility of this important signaling pathway in adult axolotls.
Thus PFA fixation allows accessibility of the IgGs to the cytosol, where they can bind their antigens, but not to the lumen of the organelles of the RSP.
These modifications change the secondary structure of the histone protein tails in relation to the DNA strands, increasing the distance between DNA and histones, and thus allowing accessibility of transcription factors to gene promoter regions.
Freud considered dreams the "royal road to the unconscious," allowing accessibility to parts of the psyche inaccessible through conscious, everyday thought.
An LCR holocomplex is formed to allow the accessibility of transcription and chromatin remodeling factors to the locus, thus providing a high local concentration of the relevant trans-acting factors for efficient transcription.
In order to allow complete accessibility of substrates to the inner mitochondrial membrane enzymes, samples were freeze-thawed three times.
In addition, MOFs can be used as catalyst supports that allow for the recycling of metallic species and also prevent the contamination of the final products.[ 4] However, for a MOF to be a suitable catalytic support it must be stable under the reaction conditions and allow no leaching of the active species, whilst still allowing full accessibility of the starting materials to the reaction site.
On nanostructured substrates, the cell adhesion-mediating molecules, such as fibronectin, vitronectin, or collagen, are adsorbed in an appropriate geometrical conformation, which allows good accessibility of specific sites in these molecules (e.g., RGD-containing oligopeptides) for cell adhesion receptors.
Sinusoids are lined by thin endothelial cells that have openings through which fingerlike projections (microvilli) of the hepatocytes extend, allowing direct accessibility of the hepatocyte to the bloodstream in the sinusoids.
These studies indicated that the WEx pretreatment was capable of producing high-sugar yields through effective degradation of hemicellulose-lignin linkages, thereby allowing easy accessibility of the cellulosic components for enzymatic action [23, 24].
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