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Thus, it is also possible that dividing tissues for different types of analyses may have resulted in allocation of tissue for PCR that did not capture the active lesion or contained insufficient numbers of fungal elements.
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The investigator (BS) was blinded as to group allocation of the tissue section.
Careful allocation of adjacent tissue samples from within a specimen to discrete groups should be employed to ensure sampling consistency is as high as possible, particularly when two different outcome measurements are compared as in the present study.
To account for these growth costs of maturation prior to age 6 years, the percentage reduction in annual growth rate was assumed to be equal to the proportional allocation of body tissue to gonads, as determined from estimates provided by McIntyre and Hutchings (2003).
International tissue brokers and stock market listed tissue processors and distributors are emerging, with far-reaching consequences for the allocation of human tissues.
Ideally, the procurement and allocation of human tissues and cells should be controlled and facilitated by (inter)national non-profit organisations, comparable to organ donation and transplantation foundations such as Eurotransplant and Swiss Transplant.
Condition index (CI), which relates the flesh weight to the amount of shell, is an important measure of the physiological status of mussels and the relative allocation of resources to tissue or shell growth [57], [58].
Discordant results were observed in 23 LNs (5.8 %), and these were mainly the result of tissue allocation bias and/or low CK19 protein expression.
In contrast, there is an inherent difficulty in attempting to validate OSNA assays by comparing them with histopathology of the same SLN because of tissue allocation bias (Snook et al, 2011).
As the LN blocks used for the OSNA assay and histological examination were obtained from different parts of the LN, discordant results between the methods cannot be completely avoided for reasons of tissue allocation bias: the metastasis could be localized in the blocks used for the OSNA assay or in the blocks for histology.
This is achieved on the one hand by modifying the energy budget allocation to tissues and on the other by the direct action of insulin on different tissues.
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