Exact(3)
The allocation of outcome of suicide attempters is extremely important in emergency situations.
The previous studies noted above considered allocation of outcome according to psychiatric diagnosis, strength of suicidal feeling, support system, and severity of method.
Prospective studies also mitigate many of the problematic aspects of the retrospective case control design, such as choice of controls, recall bias, varying definitions of AED response, and potential biases in the allocation of outcome status.
Similar(57)
Exclusion criteria were equivocal or non-random treatment allocation, lack of outcome data up to one year, and duplicate reports.
In particular, the items related to randomisation, concealment of allocation, blinding of outcome assessors, flow of participants, subgroup analyses and harms of acupuncture should be more completely reported in future Korean RCTs of acupuncture.
The quality of the study report was determined by assessing concealment of treatment allocation; blinding of outcome assessors, care providers, and participants; completeness of study and follow-up; and intention to treat analysis.
Randomized controlled trials were assessed based on concealment of treatment allocation, blinding of outcome assessors, completeness of follow-up, and the attainment of sufficient power to detect significant differences.
In addition, there were no significant associations between effect sizes and measures of potential bias: randomisation sequence, randomisation allocation, blinding of outcome assessors and incompleteness of outcome data or selective outcome reporting.
Using the Cochrane Risk of Bias Tool (22), two reviewers (V.S. and A.C). independently assessed the quality (risk of bias) of each study regarding the following domains: adequacy of randomization, concealment of allocation, blinding of outcome assessors, completeness of data, selective outcome reporting, and "other bias".
To ascertain the internal and external validity of the eligible RCTs, two pairs of reviewers (BM, WH; and MSc, Mst) working independently and with adequate reliability determined the adequacy of randomisation, concealment of allocation, blinding of outcome assessors and adequacy of data analysis (was intention-to-treat-analysis performed?) (internal validity).
Selective criteria were used in three additional studies, which all considered aspects such as study design, allocation of participants, outcome and exposure assessment, as well as the control of potential confounders [ 35, 44, 45].
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