Accordingly, the participants will be randomly allocated, by computer, to one of two intervention groups or to one of two control groups.
Participants were de-identified according to gender, age and body mass index (BMI) and randomly allocated by a process of minimisation to one of two dietary groups Group 1. Mediterranean Diet experimental group (n = 85); Group 2. Habitual Diet, control group (n = 81).
All the subjects were blindly allocated by means of scratch cards to one of the two treatment groups (mesalazine or placebo) according to a computer-generated randomisation list provided by the sponsor.
The participants were randomly allocated to one of two conditions by means of a computer-generated random allocation list.
Participants were allocated by simple randomisation to one of three groups without any restrictions placed on the sequence (that is, no blocking or stratification was included in the randomisation procedure).
Participating GPs are allocated to one of three study arms by undertaking a cluster randomization on the level of the primary care units following a Stepped Wedge Design [ 36].
After baseline measurements, participants, who met the inclusion criteria, were randomly allocated to one of the study arms by a third person remote allocation system.
Participants were randomly allocated to one of 5 diets by using a parallel design.
The intervention was then randomly allocated to one of the groups by tossing a coin in the presence of observers.
Patients will be allocated to one of two treatments by a sequence of letters: A – referring to tourniquet assisted TKA and B – referring to non-tourniquet assisted TKA using sequentially numbered opaque, sealed envelopes.
