Inducing blood vessel growth can be beneficial in alleviating tissue ischemia and in synthetic graft acceptance; however, neovascularization is also responsible for supporting pathological processes such as tumor growth.
These are being widely tested in a myriad of drug delivery applications in multiple tissues, from alleviating tissue rejections from allografts, to targeting cancer cells [ 236, 237].
Together these studies suggest that CLR blockage could alleviate tissue damage and increase survival of patients with virus-induced inflammatory diseases.
By means of high performance liquid chromatography (HPLC) and atomic absorption spectrophotometry, the TCM preparation Shenfu injection was found to decrease glutamate and Ca2+ in brain tissue and reduce excitatory amino acid toxicity, effects which can alleviate tissue edema.
In addition to its direct anti-bacterial effect, it can also decrease the permeability of capillaries in the wound and alleviate tissue edema and exudation, resulting in rapid scab formation.
This was selected to reflect a tissue stress model approach to management whereby the short term use of external devices (such as taping) is advocated to alleviate tissue stress and then followed by conventional physical therapy modalities such as muscle strengthening exercises [ 35, 36].
pretreatment alleviated renal tissue morphological damage, decreased serum Cr, BUN, CYC, TNF-α and IL-6 concentrations, reduced renal tissue MDA content, increased serum IL-10 concentration and tissue SOD activity in the I/R model of rat kidneys, as 4 ml/kg EIso pretreatment.
This may suggest that if increasing kL were to be explored as a therapeutic means to alleviate calf tissue accumulation of sVEGFR1, local lymphatic flushing as induced by leg exercise may be more productive than whole-body exercise (Fig. 9A).
Comparing with the Model group, HE sections in the QFXY group showed less pulmonary consolidation, which means QFXY help alleviate lung tissue remodelling.
As CCN2 plays roles in connective tissue pathologies, targeting Ets-1 may be beneficial in alleviating pathologies of tissue remodeling and repair, including cancer, arthritis and fibrosis.
In the early phase of septic shock, hemofiltration can attenuate the inflammatory cascade, thus alleviating cell and tissue damage and reducing the mortality due to multiple-organ failure syndrome.
