Sentence examples for alleviating binding to from inspiring English sources

Examination of the complex interactions of IL6, IL6R and IL6ST by Boulanger et al. revealed that interaction of IL6 and IL6R is followed by tertiary and quaternary changes of protein structure alleviating binding to IL6ST.

Application of the sample occurred at a flow rate of 0.2 ml/min to alleviate binding.

This inhibition is alleviated upon eIF4E binding to eIF4G.

At the cellular level triptans alleviate migraine symptoms by binding to serotonin 5-HT1b, d and f receptors along pain signaling circuits and are effective due to high receptor specificity and disease specificity [53].

At NEB TPX2 alleviates this inhibition by binding to Aurora A and blocking PP1 access [ 42,43].

cAMP regulates PKA activity by binding to Bcy1, alleviating its inhibitory activity on the catalytic subunits.

There is now evidence that TNFα can also improve remodeling and hypertrophy and alleviate inflammation and fibrosis upon binding to the TNFR2 receptor subtype or regulation of TNFR1 signaling, in cardiomyocytes, or indirectly after induction of GM-CSF secretion by endothelial renal cells, or influencing cardiac immune cell phenotypes2,25,26,27,28,29.

Activated GTP-bound Rho proteins bind to the GTPase-binding domains and occlude DAD binding to DID, thus alleviating its inhibitory influence over the FH2 domain (Goode and Eck, 2007).

We concluded that extra copies of Mia1p-MutNES4 protein could partially alleviate the need for tight Alp14p binding to ensure nuclear localization of Alp14p during mitosis.

5 The DRF contain an N-terminal Rho GTPase binding domain (GBD) which, upon binding to a Rho family GTPase, alleviates autoinhibition of inactive DRF.

A special class of LEA proteins (group II) known as dehydrins has been shown primarily to play important roles in alleviating salt and other abiotic stresses through their protective action by binding to macromolecules [ 29, 31- 35].