Sentence examples for alleviate the activation from inspiring English sources

Knockdown of IRE1 α did not alleviate the activation of JNK, indicating that IRE1 α may not be responsible for regulating the activity of JNK pathway in baicalein-induced ER stress.

The hepatocyte IKKβ prevents chemical carcinogenicity by alleviating the activation of liver macrophage, which produces mitogens that drive the compensatory hepatocyte proliferation, and reducing hepatocyte ROS accumulation and apoptosis [19].

Combination therapies with PI3K inhibition have been shown to enhance the effect of MEK inhibition within basal subtype breast cancer cells by alleviating the compensatory activation of PI3K/AKT that occurs with MEK inhibition [ 109].

In addition, silencing of PTP1B or PTEN using lentivirus-mediated shRNA expression significantly alleviated the suppressed activation state (phosphorylation) of AKT in MDFs treated with IGF-1 in the presence of rotenone (Fig 7C).

Furthermore, in the study of Reuter et al., the results infer that NTG promotes NF-кB activity and inflammation, and administration of parthenolide can alleviate the impairment by deactivating the activation of NF-кB and expression of iNOS [45].

75 These new vectors should decrease or alleviate the risks of proto-oncogene activation by insertional mutagenesis.

Modified fragmentation regimes have been introduced such as (a) NL triggered MS3 or (b) multistage activation (MSA), which alleviate the neutral loss issue commonly found with such instrumentation.

Modified fragmentation regimes have been introduced, such as (a) NL triggered MS3 or (b) multistage activation (MSA), which alleviate the neutral loss issue.

For example, Zhang and Yan devise an effective convolutional neural network to estimate air's quality based on photos by a modified activation function to alleviate the vanishing gradient issue [43].

So, the inhibition of UPS is enough to alleviate the adverse effects of NF-kB activation on the development of DN.

Its activation is required to alleviate the effects of ER stress and is highly conserved from yeast to human.