In contrast, primary food allergy mainly affects children, is frequently characterized by severe symptoms, and the sensitization process, which takes place in the gastrointestinal tract, is mediated by the food allergen itself [2], [3].
As explained above, there are two distinct processes involved in the development of a food allergy, sensitization and elicitation.
According to the sensitization process, this disease can be divided into primary and secondary food allergies, affecting 9.4% and 5.5% of the population, respectively [1].
For instance, residents of Southern states had more sensitization to indoor allergens, as well as more food allergies in people ages 6 and older, while outdoor allergy sensitization was more prevalent in the Western states.
As such, the sensitization process on which the theory was based is neither intrinsic nor extrinsic sensitization.
Recently, Larsen et al. (2007) reported that long-term inhalation of DEHP together with an allergen resulted in allergy sensitization only in concentrations of 13 mg/m.
72 In a mouse model, difference in the timing of LPS exposure led to totally opposite responses: protecting against sensitization if exposed early in the sensitization process; exacerbating inflammation if exposed after the sensitization process.
Different sensitization processes may induce different severities of antigen reactions.
Allergy and Sensitization during Childhood Associated with Prenatal and Lactational Exposure to Marine Pollutants.
C ontext: Latex allergy and sensitization have been an important problem facing health care workers.
However, it is also very clear that the development of allergy and sensitization is not simple, and the mechanisms for allergy development are mainly unknown.
