Sentence examples for allele expression patterns from inspiring English sources

To determine whether MHC class I allele expression patterns could explain the variable progression to SIV-induced CNS disease, we established which MHC class I alleles were expressed by 63 pigtailed macaques and then compared MHC class I allele expression with CNS disease outcome following SIV infection.

We have however tested many more tissues and found the same allele expression pattern favouring the paternal allele in many tissues (Table  4).> -wrap-foot> Note phase could not be determined for all SNP tested.

Genomic imprinting is a well-studied form of parent-of-origin-dependent gene expression that produces strongly biased allelic expression patterns in offspring according to the parental source of the inherited allele.

As sequence variants that distinguish two alleles are necessary to draw inferences on allele specific expression patterns, we surveyed all genes containing heterozygous SNPs in accordance with previous approaches [ 19, 20].

Since there is very limited knowledge about allele specific expression patterns we chose to only present SNPs with very high quality and having a estimated minor allele frequency in our short reads of at least 0.25.

Meg6 and Meg12 did not exhibit allele specific expression patterns.

Integrating RNA-Seq with whole genome sequencing allowed us to explore RNA editing and allele specific expression patterns in primary human cells.

They demonstrate that allele specific expression patterns within genes and across tissues can be extremely divergent and complex, when looking at multiple SNP in many tissues.

Therefore it has been successfully applied to identify differentially expressed genes [ 11] and to characterize allele-specific expression patterns [ 12, 13].

The parental allele-specific expression patterns of H19 and Igf2 were normal.

Two aspects of the allele-specific expression patterns we observe may be relevant to incomplete penetrance of a number of inherited diseases.