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Limitations of this analysis include the following: meta-analyses could not be performed on a number of the endpoints due to a lack of multiple RCTs examining that endpoint and even though the search methodology was comprehensive, we were not 100% confident that all trials were identified.
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It is also feasible that not all published trials were identified, although if publications were available beyond the comprehensive search strategy used in this study, their lack of visibility presents an additional barrier contributing to resource wastage.
All of these trials were identified from the SUTC Cochrane review of stroke units.
In all, 42 randomised trials were identified from the published literature (Medline 1966 2005) that compared two or more first-line combination therapies in women with metastatic breast cancer.
Almost all T2-absent trials were identified correctly (~85% wagers on 'T2 absent'); the wagers were spread across the left side of the scale, with a small peak at €0.60 and a pronounced peak at €0.20, suggesting that participants were often uncertain of their decision.
Seven SP-IPTi trials were identified, all were undertaken in Sub-Saharan Africa between 1999 and 2008.
Ninety-one trials were identified.
Results: Five trials were identified.
Data Synthesis: Eighteen trials were identified.
Eleven trials were identified with 373 randomized participants.
Five relevant study trials were identified, involving 117 participants.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com