Sentence examples for all susceptibility from inspiring English sources

We computed the a posteriori probability of the different association types with respect to ALL susceptibility in all sample groups (Additional file 7).

Eight ARID5B SNPs were associated with both ALL susceptibility and relapse hazard; the alleles related to higher ALL incidence were always linked to poorer treatment outcome and were more frequent in Hispanics.ARID5B polymorphisms are important determinants of childhood ALL susceptibility and treatment outcome, and they contribute to racial disparities in this disease.

In the T-cell lineage, only the gender of the patient has a high probability of direct association to ALL susceptibility (0.85), where males have significantly higher odds of developing ALL than women (OR = 2.28, C.I. 95%: 1.32 – 3.93).

Multivariate analyses in Hispanics identified an additional SNP associated with ALL susceptibility independent of rs10821936.

Recent reports of germline ETV6 variations associated with substantial familial clustering of haematological malignancies indicated that this gene is a potentially important genetic determinant for ALL susceptibility.

We sought to determine the contribution of ARID5B single nucleotide polymorphisms (SNPs) to racial disparities in ALL susceptibility and treatment outcome.We compared the association between ARID5B SNP genotype and ALL susceptibility in whites (> 95% European genetic ancestry; 978 cases and 1,046 controls) versus in Hispanics (> 10% Native American ancestry; 330 cases and 541 controls).

We determined the relationships between ARID5B SNP genotype and ALL relapse risk in 1,605 children treated on the Children's Oncology Group COGG) P9904/9905 clinical trials.Among 49 ARID5B SNPs interrogated, 10 were significantly associated with ALL susceptibility in both whites and Hispanics (P <.05), with risk alleles consistently more frequent in Hispanics than in whites.

Because of the possible roles of IL-15 in ALL development, we performed case control studies to investigate the association between the five SNPs in human IL-15 gene and adult ALL susceptibility in a Chinese population.

Significant differences in take-all susceptibility between the accessions tested were detected in all four field trials.

In order to identify the mechanism of this specific pB-ALL susceptibility due to Pax5 heterozygosity under exposure to infections, we characterized both B-cell development in healthy and B-cells in leukemic Pax5+/− mice [ 2].

To define the limit of c-ALL susceptibility within the HLA region, we have compared HLA-DQB1 allele frequencies in a cohort of 62 children with c-ALL with 76 newborn controls, using group-specific polymerase chain reaction (PCR) amplification, and single-strand conformation polymorphism (SSCP) analysis.