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All samples used in this study were mechanically exfoliated from bulk crystals.
All samples used in this study were discarded de-identified tissues.
All samples used in this study were purchased from PromedDx (Norton, MA).
All samples used in this study are described in Table 1.
All samples used in this study came from animals that were captured, handled, and released according to relevant national and international scientific guidelines.
The authors declare that all samples used in this study were encoded anonymously and that none of the patients had explicitly refused to participate in research.
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To test the effect of MEK inhibition in T-ALL, human T-ALL cell samples were co-cultured with MS5 or MS5-DL1 stromal cells directly after isolation from patients or after injection in immunodeficient mice (see Supplementary Table S2 for a description of the 26 T-ALL samples used in this study) in the presence of a MEKi (U0126, PD98059 or PD184352).
Mapping statistics and details of all the samples used in this study are contained in Supplementary Data 1.
Flowchart of data processing and samples used in this study.
Supplementary Table 1: Coral samples used in this study.
Detailed information of the samples used in this study is provided in Supplementary Table S1.
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