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Since there is no all-round method which could cover conditions of all AMPs, it was not surprising that the method was not optimal for the CAP peptides.
To this end, each dosing region was assigned a rounding method by linkage to a specific data table within the ADM database schema that defined a type of rounding behavior.
The GBG was calibrated using the swing round method, and measurement uncertainties on chordal tooth thickness and total pitch deviation Fp were determined to be 0.9 μm and 1.4 μm, respectively.
FlowgramFixer outperformed the baseline rounding method for all quality thresholds, with a 2.8 4.8% increase in the number of high-quality aligned reads.
A significantly better rounding method that uses a technique called telescoping is presented in this paper.
Jain's iterative rounding method and its variants give the best approximation guarantees known for many problems in the area of network design.
We construct a family of examples such that the standard LP relaxation has an extreme-point solution with infinity norm ≤Θ(1)/√k, thus showing that the standard iterative rounding method cannot achieve an approximation guarantee better than Ω √k).
The workflow of the proposed two-round method is shown in Figure 1.
The baseline rounding method yielded 3 537 723 uniquely mapped reads, whereas FlowgramFixer yielded 3 788 697—an increase of 250 974 reads (7.1%).
We proposed in this paper a two-round method to quantitatively model the DNA binding affinity landscape.
– Truncated normal regression (carried out using mi impute truncreg), with the lower and upper limits specified as the same limits used for the post-imputation rounding method.
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