The pattern of interconnections necessary for a competitive interaction mechanism, where all representations within the parameter space are about equally interconnected with all other representations in the map (cf. Ref. [4]), is easily realized within a circular functional map, but is much more difficult to implement in a map with a linear functional gradient.
The universe, as it (actually) is, is not a representation but includes all representations, along with everything else.
In such cases it would make sense to cross-validate all these other representations with the connection table.
Otherwise, all logical representations with a minimal number of terms that give the required values for the control function were computed using the Quine-McCluskey Algorithm [ 23].
This calculation employed an all-atom representation with an explicit solvation model, combined with a novel, customized steering potential derived from our cryo-EM maps (See 'Materials and methods' and Figure 2 figure supplement 1).
The NLS measure is measured for all representations and shown along with the other parameters of interest in Table 2. Table 2 Signal Characteristics of R1, R2, R3, R4, R5, R6, and R7.
The multiscale computational approach that combines elements from the mean-field level coarse-grained representations, with all-atomistic MD simulations, was shown here to be very well suited for the computational prediction of the pattern of PIP2 lipid distribution around STX constructs in the steady state.
In addition, the activity list as the core of all representations evaluated may be exchanged with another widespread encoding for inducing activity priorities, the so-called standardized random key representation, Debels et al.
The subcategory R ′ consists of all regular representations with no indecomposable direct summand in T ∞, or equivalently, it is the full subcategory of all representations M such that M α is bijective.
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