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If, as Sperber suggests, one thinks of all possible transformations in a space of possibilities, probabilities will tend to cluster in some points of this space.
In view of the expanding amount of known reactions, it has become more and more difficult to envision all possible transformations that could occur in a studied system.
To overcome these difficulties the idea of the transformation enumeration approach is to start with one fully-grown molecule to which one applies all possible transformations such that all the structural isomers of the initial molecule are generated.
Further, assume that M1, M2,…, M n are all possible transformations that map G c 1 into G c 2, i.e, M i (G c 1 ) = G c 2. Then the optimal cost of the optimal transformation, M ′, is given by c(M ′ ) = min{ c(M i )|1 ≤ i ≤ n}.
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All possible transformation size-restricted MMPs and RECAP-MMPs were calculated using an in-house implementation of the algorithm by Hussain and Rea that utilizes the OpenEye toolkit.
It should be noted that all the possible transformations of the unmapped reads are passed to the next stages.
Consider the value of data-driven decision making as a possible transformation for a business.
The finding of increased activity, as indicated by a SUVmax value from 6 to 29, clearly suggests a possible transformation from differentiated thyroid cancer to ATC.
The auditory pathway leading through aPN1, vPN1, and pC1 shows a possible transformation of song representation.
Assumptions were based on expert opinions to provide a possible transformation algorithm.
Not all possible urban transformations may lead toward sustainability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com