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A test suite is considered to be good if it distinguishes between the original description and all of the (functionally non-equivalent) mutants.
All of the functionally enriched GO terms identified thus far for those genes up-regulated at 24 and 48 hrs p.i. appeared to be closely involved in either genomic transcription (i.e., TFs, sequence-specific DNA and/or double-stranded RNA binding, oligopeptide transporter, and protein dimerization) or inflammatory responses (Figure 4A).
In silico analyses revealed that all of the functionally characterized human Cx50 missense mutations alter highly conserved residues (Supplemental Figure 1; multiple sequence alignment provided as supplementary text).
By contrast, Ire1 is well conserved in S. pombe, with all of the functionally important hallmarks identified in other eukaryotes, including its ER lumenal unfolded protein sensing domain and its cytosolic kinase and RNase domains.
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To address this concern, we run several additional passes through the group in which each subject's warp field is refined by functionally (pair-wise) registering it to its leave-one-out atlas, defined as the average of all of the other functionally normalized subjects in the group.
The 2-D theory is derived in invariant variational and differential forms and governs all the types of vibrations of the functionally graded micropolar shell.
All it can give us is a rendering of the functionally insane insanity being the sworn foe of the coherent.
c EDS analysis of the functionally graded layer.
Furthermore, we analyzed the coverage of the functionally annotated transcripts.
First, protein sequence comparison showed that Tc-MYBPA was most similar to the grape PA transcriptional regulator VvMYBPA1 and shared the conserved motifs of all the other functionally characterized R2R3-MYB PA synthesis regulators.
Second, comparisons between D. melanogaster and D. hydei indicate there have been no gene losses within the complex since the common ancestor of these species [ 20] suggesting that all of the genes are functionally important and maintained by stabilizing selection.
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