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These models operate at all levels of specificity.
By contrast, the conventional AUC analysis indiscriminately summarizes the performance of a marker at all levels of specificity.
Figures 2 and 3 shows the differentially regulated biological processes from all levels of specificity related to one of the up-regulated and one of the down-regulated processes, ion transport and protein ubiquitination, respectively.
When GO terms from all levels of specificity were considered, several differentially regulated pathways (GO terms) were identified both in normal and tumour tissue of asbestos-exposed patients as compared to the non-exposed (Additional files 1 and 2).
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A ROC analysis was completed to compare all levels of sensitivity and specificity.
All but three filters achieved a level of specificity above 85%.
All thresholds have comparable levels of specificity and accuracy.
Centrally, an Oracle database has web interfaces allowing multiple user-types, including the general public, to mine de-identified information from all of the sites with three levels of specificity and granularity as well as to request tissues through a formal letter of intent.
iBBiG was able to identify all clusters in a simulated meta-GSA dataset with high levels of specificity and sensitivity.
Queries to the Obama and McCain campaigns, as well as the Democratic and Republican National Committees, yielded differing answers and levels of specificity.
Cornish identified four such levels of specificity: tracks, scripts, protoscripts and metascripts.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com