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Statistical significance for all data was set at P < 0.05.
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The false discovery rate for all the proteomic data was set at 0.01.
Significance level for all statistical data was set to 0.05.
For all groups, efficacy data were set to missing after initiation of rescue medication.
For all amplification plots the baseline data were set with the automatic cycle threshold function.
The weights of all data points were set equal after flattening square values of each data point.
All data modes were set to log, and the forward scatter detector level was set to E-1.
Efficiency: all data are automatically run through pre-set procedures.
DOI: http://dx.doi.org/10.7554/eLife.03665.007 All data sets were recorded using 300 keV electrons.
All data set were rasterized to 5 m × 5 m grid cell.
This process was iterated until all data sets were used in the training and testing sets.
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