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All data was generated using a FACSCalibur (Becton Dickinson) and analyzed using CellQuest (Becton Dickinson) and Summit V4.3 software (Dako).
All data was generated for previously published studies, without consideration for its present use in this study of preprocessing algorithms.
All data was generated using MAS 5.0 (Affymetrix, Inc., Santa Clara, CA) with the same detection call cutoffs used to determine presence or absence for each probeset.
All data was generated using a Coulter Cytomics FC500 analyzer, collecting 20,000 events per sample, and analyzed with FlowJo software.
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NOTE: all data were generated from the general information questionnaire; numbers may not add up exactly where individual participants have refused to answer specific questions.
F2 generations were used and all data were generated from littermates.
All data were generated using a custom two-dimensional model that describes convection and diffusion in a system of two fluids running side-by-side in a duct.
All data were generated and analysed using Matlab (v.6.5).
Importantly, serum half-life, biodistribution, and stability are all evaluated in the same mice, which reduces the number of research animals utilized (Figure 6) and all data is generated on a single piece of equipment, which reduces capital equipment costs.
All data were generated at least in triplicate and expressed as mean ± SD.
All data were generated in triplicates and expressed as median +/- SD with the 25 75 percentiles.
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