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All data was evaluated and interpreted with Xcalibur Software Thermo Scientificc, Dreieich, Germany).
Statistical significance of all data was evaluated using the Student's t-test, p < 0.05.
The statistical significance of all data was evaluated by ANOVA post hoc LSD using IBM SPSS Statistics Version 20 (IBM Corp., New York, USA).
All data was evaluated using a one-way ANOVA followed by post-hoc Tukey's or Dunnet's analysis of the means, using Prism 6 (GraphPad Software, La Jolla, CA).
All data was evaluated in terms of the intention-to-treat approach (ITT); last observation carried forward (LOCF) was used as a method of ITT and data are presented accordingly [ 20].
All data was evaluated using a Student's t test or one-way ANOVA followed by post-hoc Tukey's analysis of the means, using Prism 6 (GraphPad Software, La Jolla, CA).
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All data were evaluated using the R software package R Core Team [16].
All data were evaluated by at least 3 independent experiments.
All data were evaluated by two-way factorial analysis of variance (ANOVA) with treatment differences among means tested at P = 0.05 by Tukey post-hoc test.
All data were evaluated using SPSS.
Clinical data were kept unavailable during the laboratory analysis until all data were evaluated.
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