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Certain insertions were manually removed after sequence alignments to maximize alignable regions prior to calculating the polymorphism parameters.
Specifically, our algorithm, called AGE for Alignment with Gap Excision, finds the optimal solution by simultaneously aligning the 5′ and 3′ ends of two given sequences and introducing a 'large-gap jump' between the local end alignments to maximize the total alignment score.
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Instrumentation constructs are designed to maintain spinal alignment, to maximize the likelihood of achieving solid arthrodesis, and to minimize the probability of developing a junctional syndrome.
Using a 3-dimensional computer-aided design (3D CAD) program, we investigated the optimal rotational baseplate alignment to maximize peripheral locking-screw purchase.
Once attached, epicardial cells direct myocardial cell proliferation, maturation, mechanical/electrical coupling, and cellular alignment to maximize contractile force (Weeke-Klimp et al., 2010).
Local alignments align subnetworks to maximize the local alignment score.
In addition, the search model was set to the "local alignment" mode to maximize for search sensitivity.
In contrast to short-read alignment algorithms that tend to maximize global alignments, longer-read alignment algorithms aim to find local matches because longer reads are more prone to structural variations and map over misassemblies in the reference sequence.
The results of this alignment were filtered to maximize true (non-paralogous) loci shared between parents.
The aim of any alignment procedure is to maximize the homology.
Different from LNA, global network alignment (GNA) aims to maximize the overall match between the input networks.
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CEO of Professional Science Editing for Scientists @ prosciediting.com