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A total of 97.4% alignments out of the total satisfied these conditions.
The alignment error rate, which is the fraction of wrong alignments out of confident mappings in simulation (see also Section 3.2), only increases from 0.08%to0.11%1%.
Due to the restriction on the alignment size imposed by the Pfold server, only 27 alignments out of 36 could be run on Pfold.
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All mammalian sequences were extracted and multiple sequence alignments carried out using CLUSTALW 2.0 [ 18].
A visual inspection of the alignments pointed out a possible explanation to these results.
Individual inspection of these gene alignments ruled out possible misalignments or chimeric structures.
Whereas ProSup's filter detected the mis-alignment illustrated in Fig. 2, it also detected 18 other potential mis-alignments out of 74 residues aligned using its standard method, implying either that the Ca method was unsuccessful in determining correct alignment over as much as 24% of the protein, or that the filter had a rather high false positive rate.
Paris-Roubaix is the symbolic arrival of spring in northern Europe, when riders whack the alignment out of their spines and their bicycles.
c Ambulatory limb alignment out of frame.
The NW step filters about two-thirds of incoming hits, meaning that previous filters have efficiently ruled out most false positive alignments—one alignment out of three that enters the NW step is valid.
Multiple sequence alignment was carried out using the TCoffee alignment program.
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CEO of Professional Science Editing for Scientists @ prosciediting.com