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However, often researchers need to visualize these read alignments in the context of genome annotation.
MagicViewer (Hou et al., 2010) is also capable of displaying large-scale short-read alignments in the context of annotations.
BamView was subsequently incorporated into Artemis, providing the functionality to view these read alignments in the context of the nucleotide sequence and genomic features.
MagicViewer [ 19] is also capable of displaying large-scale short read alignments in the context of annotations and provides a pipeline for genetic variation detection, annotation and visualization.
LookSeq [ 16] and Genome browsers including Integrative Genome Viewer [ 17] (IGV), Integrated Genome Browser [ 18] (IGB) and GenoViewer (http://www.genoviewer.com), have been developed to visualize these read alignments in the context of genome annotation.
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We then parsed out the TM profiles for the authority protein and the aligned MoLFunC, and visually superimposed them on the plot so we could see the alignment in the context of the topologies.
We show BFAST can achieve substantially greater sensitivity of alignment in the context of errors and true variants, especially insertions and deletions, and minimize false mappings, while maintaining adequate speed compared to other current methods.
Results: We present the first application which allows visualization of conserved regions in a multiple sequence alignment in the context of codons.
This process has many of the hallmarks of interactive alignment in the context of joint action and dialogue (Garrod & Pickering, 2009).
The intronic architecture of the GHF5 endoglucanase genes was mapped onto a multiple protein sequence alignment in the context of the overall secondary structure of an archetypal GHF5 endoglucanase (See additional file 3), but there appears to be no general correlation.
Consequently, the relatively permissive W = 16 was maintained in order to facilitate the identification of alignments, particularly in the context of searches of genomic (MF) databases against a database (Os_CD) which consists of predicted coding sequences.
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