Sentence examples for alignment to multiple from inspiring English sources

The advantage of using a trie is that an alignment to multiple identical copies of a substring in the reference is only done once since they collapse on a single path in the trie.

This strategy is also used to solve alignment to multiple identical copies in the reference genome sequence efficiently, which is superior to the hash table-based algorithm.

The reasons for dropping loci were either lower separation between read count clusters or read alignment to multiple locations in the genome.

Only the two most significant alignments were retained in an attempt to avoid spurious alignment to multiple genes from different stickleback linkage groups (for example due to similarity of genes from the same gene family).

But in polyploid species, the existence of homoeologous sequences makes it difficult to differentiate the allelic SNPs from the homoeologous and also paralogous sequence differences, because multiple sequence reads can align to the same genomic location or an individual sequence read can show significant alignment to multiple genomic locations.

C-Sibelia addresses this problem by first decomposing genomes into synteny blocks, using the iterative de Bruijn graph algorithm described in Minkin et al. This step separates linear operations (indels, substitutions) from non-linear operations (rearrangements) and thus allows us to apply global alignment to multiple instances of each synteny block.

Finally, we assigned to each transcript the most frequent gene symbol from the corresponding BLAST alignments to multiple species.

In a second stage, we merge alignments to multiple pseudogenomes and assign an origin to every read.

Restoring fragment alignments to multiple positions does not cause inflation in abundance level estimation because transcriptome inference methods such as Cufflinks already consider the shared alignments.

Matches were also screened for alignments to multiple homologous prohormone genes that could indicate gene duplication events in the pig genome.

Certainly, our method can be easily extended to multiple species, in the similar way as extending pairwise alignments to multiple alignments (the conservation score will be defined as the sum of pairwise conservation score).