Sentence examples for alignment to human from inspiring English sources

SNPs surpassing an arbitrary threshold of significance (P < 0.005, ~ top 0.5%% of markers) were aligned to an Atlantic salmon reference transcriptome, identifying 109 SNPs in transcribed regions that were annotated by alignment to human, mouse and zebrafish protein databases.

Comparative genomic alignment to human sequence revealed that the hydroxysteroid (17-beta) dehydrogenase 6 homolog (HSD17B6), which is known to be involved in steroid metabolism [ 45], is expected to be located within this region.

The PhastCons plot from the UCSC 99 vertebrate whole-genome alignment to human showed a conserved region within the terminal exon, which includes the approximately 300-nt region that is conserved between pigs and humans (fig. 3).

We chose to leave in our final data set all microsatellites found in suspicious alignments because only suspicious alignments to human chromosome 1 have been identified to date.

KLK genes were annotated based on alignments to human RefSeq cDNA and protein sequences with the BATI algorithm (Blast, Annotate, Tune, Iterate) using four Perl scripts Tbex, BlastSniffer, GeneTuner, and bgmix available at http://degradome.uniovi.es/downloads.html (last accessed December 10 , 2012.

The assembled BAC sequences were annotated for gene content based on alignments to human RefSeq mRNA (or species-specific mRNA, if available) sequences using Spidey (http://www.ncbi.nlm.nih.gov/spidey) and BLAST [ 61].

We then aligned this structure-based alignment to the human UGT1A1 sequence based on the predicted vertebrate UGT secondary structure profile.

NGS reads were filtered for exclusion of human sequences using Bowtie2 high-sensitivity local alignment to the human hg38 reference database at default parameters followed by BLASTn alignment to all primate sequences in NCBI nt at an e-value cutoff of 10−8 prior to deposition into the NCBI SRA database.

Sequence reads were additionally filtered for exclusion of human sequences by both BLASTn alignment at an e-value cutoff of 10-5 and Bowtie2 high-sensitivity local alignment to the human hg38 reference database.

Read alignment to the human genome assembly hg19 using the novoalign alignment tool (Novocraft Technologies).

The Burrows-Wheeler Aligner (Li and Durbin, 2009) was used for alignment to the human reference genome build UCSC hg19 (Grchg19.