Sentence examples for alignment to guide from inspiring English sources

Although the results of this investigation clearly show that it is possible to produce small areas (1 cm2) of collagen fibrils with enough alignment to guide fibroblasts, there is evidence that thin film instabilities are likely to be a significant barrier to producing organized collagen fibrils over larger areas.

Using primary-sequence alignments to guide our enzyme engineering, we have successfully introduced allosteric-inhibition sites in four classical PTPs PTP1B, PTPH-1, FAP-1, and HePTP from four different PTP subfamilies, suggesting that our sensitization approach can likely be applied widely across the classical PTP family to generate biarsenical-responsive PTPs.

We also used the protein alignments to guide a nucleotide sequence alignment using tranalign from the EMBOSS package (Rice et al. 2000).

Proteny could be generalized towards any number of species by a progressive heuristic similar to the star multiple alignment heuristic (Altschul and Lipman, 1989), which uses a central sequence with pairwise sequence alignments to guide the multiple alignment.

We used simulated alignment data to guide the design of our ncRNA discovery pipeline and estimate the corresponding false-positive rate.

Figure 1B shows the multiple sequence alignment used to guide the modeling of the best 3D structure obtained for the hIKK-2 kinase domain, which is shown in Figure 1A.

Protein sequences were aligned, and the resulting amino acid sequence alignments were used to guide the alignment of nucleotide coding sequences (CDSs).

Pairs of orthologous amino acid sequences were aligned using ProbCons 1.12 [ 75], and the resulting alignments were used to guide the alignment of the corresponding CDSs.

These alignments were used to guide the alignment of the CDS sequences.

Protein sequence alignments were used to guide an alignment of encoding nucleotides using the program tranalign http://bioweb2.pasteur.fr/docs/EMBOSS/tranalign.html.html

The resulting filtered protein alignments were used to guide the alignment of the corresponding CDSs using an in-house BioPerl script.